Sarah Silverman is known for breaking taboos in her comedy. Her new off-Broadway musical The Bedwetter, adapted from her 2010 memoir of the same name, centers on the most humiliating part of her childhood: wetting the bed every night until she was about 16.
Melissa McCarthy stars in the new film Can You Ever Forgive Me? as a biographer turned literary forger. She talks about growing up on a farm, her early comedy act. her breakout role in Bridesmaids, and playing Trump's former press secretary Sean Spicer on Saturday Night Live.
After Tig Notaro stand-up set about having cancer went viral, she released the comedy special Boyish Girl Interrupted, and co-wrote and starred in the semi-autobiographical Amazon series One Mississippi. In 2015, she married actress Stephanie Allynne, and they now have twin boys.
Comic and actor Louis C.K. created and stars in the new HBO comedy series Lucky Louie. C.K. has been a writer for David Letterman, Conan O'Brien, Chris Rock and Saturday Night Live. He also wrote, produced and directed the film Pootie Tang. Lucky Louie airs Sunday nights at 10:30 p.m. ET on HBO, following Entourage.