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06:02

In 'Handsome Harry,' Guilt Plays A Starring Role.

Bette Gordon's drama stars Jamey Sheridan as a broken man trying to make amends for a terrible crime he helped commit 33 years ago. Critic David Edelstein says Sheridan — along with co-stars Steve Buscemi and Aidan Quinn — are beyond praise in this dark and moving revenge story.

Review
05:53

A Novel Tallies The Real Cost Of Health Care.

So Much For That, Lionel Shriver's new novel, is about a middle-aged man forced to give up his dream of retirement on a tropical island when his wife falls ill and he's forced to go back to work to keep his employee health insurance. Critic Maureen Corrigan says the novel "acknowledge[s] the dramatic depth that fiction can bring to the debate over current events."

Review
27:28

Re-Examining The Father Of Modern Surgery.

William Halsted is credited with creating the United States' first surgical residency program and transforming the way operating rooms are sterilized. He was also a morphine addict. Plastic surgeon Gerald Imber details Halsted's dual lives in the new biography Genius on the Edge.

Interview
44:30

Temple Grandin: The Woman Who Talks to Animals.

Temple Grandin is one of the world's greatest animal behaviorists. She is also autistic — and has put that to work for her. Grandin has written several books on animals, including Animals in Translation: Using the Mysteries of Autism to Decode Animal Behavior. This weekend, HBO will premiere a made-for-TV movie based on her life.

Interview
43:01

'Henrietta Lacks': A Donor's Immortal Legacy.

In 1951, Henrietta Lacks died after a long battle with cervical cancer. Doctors cultured her cells without permission from her family. The story of those cells — known as HeLa cells, in Lacks' honor — and of the medical advances that came from them, is told in Rebecca Skloot's book, The Immortal Life of Henrietta Lacks.

Interview
16:08

'Get Me Out': Making Babies Through The Ages.

Mare's-urine cocktails? Do-it-yourself forceps? Randi Hutter Epstein's new book Get Me Out: A History of Childbirth From the Garden of Eden to the Sperm Bank is full of delightful — and sometimes disturbing — anecdotes about the history of pregnancy and childbirth.

05:51

'Extraordinary Measures': The Least A Father Can Do

There's a basic tension in the true-ish docudrama Extraordinary Measures that lifts it above the formula disease-of-the-week picture. Brendan Fraser plays John Crowley, a Bristol-Myers Squibb executive with a daughter and son born with the rare Pompe disease, a cousin to muscular dystrophy that fatally weakens muscles — including the biggie, the heart.

Review
50:28

Next Up: Turning Two Health Care Bills Into One

Jonathan Cohn traveled the country in search of ordinary Americans who had been affected by America's health care crisis. The stories he found — of heart attack victims becoming casualties of overcrowded emergency rooms and diabetes patients going blind because they can't afford treatment — earned him the Harry Chapin Media Award for coverage of poverty-related issues, as well as praise from both journalism and health care professionals. They also became the core of his book Sick: The Untold Story of America's Health Care Crisis — and the People Who Pay the Price.

Interview
43:05

Wounded In Wars, Civilians Face Care Battle At Home

T. Christian Miller doesn't shy away from trouble. He has reported on conflicts in Kosovo, Israel and Iraq, among others, and the Web site he founded, ProPublica, is dedicated to covering stories with "moral force" — providing in-depth coverage of environmental, defense, and human rights issues. One story Miller has been following closely, in a series of articles titled "Disposable Army," is the fate of employees who worked for private military contractors in Iraq and Afghanistan.

21:53

In Memoriam: Sweet, Sad Rocker Vic Chesnutt

Vic Chesnutt was paralyzed from the waist down at the age of 18, but he's still a massively productive songwriter. Chesnutt has fifteen albums under his belt and his songs have been covered by Madonna, Smashing Pumpkins, and R.E.M. His new album, At The Cut, is a collaboration with Guy Picciotto of the band Fugazi. (

Obituary
44:59

Songs Of Survival And Reflection: 'At The Cut.'

Vic Chesnutt was paralyzed from the waist down at the age of 18, but he's still a massively productive songwriter. Chesnutt has fifteen albums under his belt and his songs have been covered by Madonna, Smashing Pumpkins, and R.E.M. His new album, At The Cut, is a collaboration with Guy Picciotto of the band Fugazi.

07:39

Larry David's Dysfunctional Family Reunion

The seventh season finale of Curb Your Enthusiasm capped a year-long storyline about Larry finally agreeing to a produce a reunion episode of Seinfeld when he co-created with Jerry Seinfeld. TV critic David Bianculli explains how both programs -- the show and the show within the show -- were a comedic cop and a perfect end to the season.

Review
15:44

For Wounded Soldiers, Prosthetic Help At Home

Advances in military medicine mean that more soldiers are surviving on the battlefieled, but many are coming home with missing limbs. When they come home, those soldiers turn to Colonel Paul Pasquina, medical director of the amputee program at Walter Reed Army Medical Center for the latest in in prosthetics.

Interview
17:19

An Open-Source Approach To Better Prosthetics

When Marine engineer Jonathan Kuniholm returned to his industrial-designed shop after a tour of duty in Iraq, one of his first projects was personal: He wanted to improve on the design of the prosthetics he'd been using since he lost part of his right arm in an ambush. Kuniholm and his colleagues founded the Open Prosthetics Project, an open-source collaboration that shares its innovations freely.

Interview
06:02

'The Lacuna,' Kingsolver's Vacant Return

It's been nine years since Barbara Kingsolver, author of The Poisonwood Bible, has released a new novel -- but is The Lacuna worth the wait? Critic Maureen Corrigan says this personalized perspective on the Red Scare in Mexico reflects the hidden meaning of the book's title: vacancy.

Review
44:24

Venturing Inside Bellevue's Psychiatric ER

Weekends at Bellevue is psychiatrist Julie Holland's account of her years treating patients in a New York City psychiatric ER. She says one of the hardest parts of her job was figuring out which patients were manic or schizophrenic and which were high on cocaine or methamphetamines.

Interview
43:15

Jane Mayer: The Risks Of A Remote-Controlled War

A staff writer for The New Yorker, Jane Mayer joins Fresh Air host Terry Gross to talk about what she discovered while researching her upcoming article "The Predator War." The story explores the ethics and controversies surrounding the CIA's covert drone program, in which remote-controlled airplanes target and kill terror suspects within Pakistan — a country that's a U.S. ally, not an adversary.

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