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50:30

For Zoe Kazan, 'Plot Against America' Is 'Scarily Prescient' And Personal

Actor Zoe Kazan describes her new HBO series, The Plot Against America, as "scarily prescient." The show, which is adapted from Philip Roth's 2004 novel, is set in the U.S. between 1940 and 1942, and imagines a world in which aviator Charles Lindbergh has defeated Franklin D. Roosevelt in the race for the presidency, moving the country toward fascism.

Interview
50:28

Rachel Maddow: The Fresh Air Interview

The popular MSNBC host talks about her start in broadcasting, her life and her new book Drift: The Unmooring of American Military Power, in which she argues that America's national defense has become disconnected from public oversight.

Interview
05:51

As The World Ends, A Certain 'Melancholia' Sets In

Lars von Trier's Melancholia stars Kirsten Dunst and Charlotte Gainsbourg as sisters who undergo a psychological transformation as disaster approaches. Critic David Edelstein says the film is a sublime fusion of form and content with a truly Wagnerian climax. (Recommended)

Review
27:34

Dunst: Expressing Something Blue In Melancholia

The actress stars in Lars von Trier's new psychological drama Melancholia, about depression and the end of the world. She talks about making the film and about working with Von Trier, whose controversial remarks about Hitler got him kicked out of this year's Cannes Film Festival.

Interview
19:29

You Won't Feel A Thing: Your Brain On Anesthesia.

Anesthesiologist Emery Brown explains what physicians know — and what they don't know — about the effects of anesthesia. Unlocking its mysteries, he says, will help scientists better understand consciousness and sleep — and could lead to better treatments for pain, sleep disorders and depression.

Interview
19:00

What Science Says About Aging and Depression

Charles Reynolds teaches at the University of Pittsburgh School of Medicine and directs research into late-life mood disorders; now he has co-written a book about depression in the elderly and how to treat it. It's titled Living Longer Depression Free: A Family Guide to Recognizing, Treating, and Preventing Depression in Later Life.

20:39

Listening Again to Author William Styron

Pulitzer Prize-winning writer William Styron died Wednesday of pneumonia at the age of 81. Styron's books include Lie Down in Darkness, The Confessions of Nat Turner (which won the Pulitzer) and Sophie's Choice, which was adapted into an Oscar-winning film starring Meryl Streep. His memoir Darkness Visible detailed his struggles with depression and suicidal impulses. This interview originally aired on Sept. 19, 1990.

Obituary
27:17

Kitty Dukakis Backs ECT for Depression

Former gubernatorial first lady Kitty Dukakis and writer Larry Tye discuss their new book, Shock: The Healing Power of Electroconvulsive Therapy. Dukakis, the wife of former Massachusetts governor and 1988 Democratic presidential nominee Michael Dukakis, battled depression for over 20 years. She says electroconvulsive therapy dramatically changed her life for the better.

40:41

Writer Andrew Solomon

His new book on depression, The Noonday Demon: An Atlas of Depression, (Scribner) came out of a 1998 New Yorker article. He draws on personal experience as well as interviews with patients, physicians, philosophers and drug designers.

Interview
12:46

"The Other Great Depression."

Comedian Richard Lewis. His new book is called “The Other Great Depression,” (Public Affairs, 2000) and chronicles his recovery from alcoholism. He’s an award winning stand up comic and has appeared in over twenty movies and TV shows. Currently, he co-stars in Larry David’s HBO show “Curb Your Enthusiasm.”

Interview

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