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21:35

Cancer researcher John Mendelsohn

Cancer researcher John Mendelsohn, M.D. is the president of the MD Anderson Cancer Center at the University of Texas. We will talk about new developments in cancer treatment. Mendelsohn created a new cancer drug, known as C225. The drug shows great promise in treating a number of cancers by halting the growth of cancer cells. There has been an explosion in the number of cancer drugs in recent years.

Interview
38:32

Novelist Carol Shields

Novelist Carol Shields won a Pulitzer Prize for her best-selling novel, The Stone Diaries. Her books are often about middle-class people leading quiet lives. Her other novels include Larrys Party, which won Britains Orange Prize, The Republic of Love and Swann: A Mystery. She also wrote a biography of Jane Austen as well as plays, poetry and story collections. In 1998 Shields was diagnosed with breast cancer. She is now in a late stage of the disease. Her new novel, Unless (Fourth Estate), was written after her diagnosis.

Interview
21:42

Rebuilding a Life: 'Who She Was'

Writer Samuel G. Freedman's new book is Who She Was: My Search for My Mother's Life. Freedman's mother died many years ago, when he was just 18, and as he approached his mother's age when she died, he decided to find out all about her life. The result is a narrative fueled by facts.

Interview
43:53

A Personal Stake in Beating Cancer

Dr. Sandra Horning and Dr. David Johnson are both oncologists. Horning is the current president of the American Society of Clinical Oncology, the largest group of cancer-treatment specialists. Johnson was president before her. Both of them are cancer survivors — the first to lead the 41-year-old society. Horning practices and does research on lymphomas at Stanford. She is also co-chairman of the oncology society's task force on cancer survivorship. Johnson is deputy director of the Vanderbilt-Ingram Cancer Center in Nashville, Tenn.

31:55

Saturday Night Live's Julia Sweeney

Julia Sweeney is currently performing a one-woman show called "Letting Go of God" at the off-off-Broadway theater in Manhattan. A Saturday Night Live cast alum, Sweeney also wrote and performed the 1996 Broadway show "God Said, Ha!" Her films include Pulp Fiction, Clockstoppers and It's Pat, based on her gender-confused character on SNL.

Interview
35:53

David Rieff, 'Swimming in a Sea of Death'

Diagnosed with cancer for the third time, Susan Sontag signed on for a harsh treatment regimen in hopes it would keep her alive. But it only added to her suffering. Her son, journalist David Rieff, has published a memoir about his mother's "revolt against death."

Interview
21:14

The Rev. Forrest Church, Living 'Love And Death'

Unitarian minister Forrest Church was diagnosed with terminal esophageal cancer last February. He has written and edited over 20 books since 1985. His latest, Love and Death, is a memoir that confronts the fact of death and, in the process, offers readers a meditation on the end of life.

Interview
13:05

Forrest Church And The 'Valley Of The Shadow'

Unitarian minister Forrest Church believed that the knowledge that we must die makes us question what life means. Church, who died Sept. 24, 2009 after a long battle with cancer of the esophagus, was the author of Love and Death: My Journey through the Valley of the Shadow.

Obituary
06:18

Clunky Characters, Cancer Characterize 'Big C.'

The new Showtime series stars Laura Linney as a wife and mother battling cancer. Critic David Bianculli says the leads (Oliver Platt among them) are just fine, but the subsidiary characters could use a second look. Also back for another season on Showtime: Weeds, which makes The Big C look limp by comparison.

Review
37:42

An Oncologist's Pulitzer-Winning Cancer Biography.

Oncologist Siddhartha Mukherjee chronicles how our understanding of cancer has evolved in his new book The Emperor of All Maladies: A Biography of Cancer.

This interview was originally broadcast on Nov. 17, 2010. Siddhartha Mukherjee recently received the 2011 Pulitzer Prize for General Nonfiction for 'The Emperor of all Maladies.'

43:49

Gordon-Levitt, Reiser Tackle '50/50' Odds

Screenwriter Will Reiser coped with his cancer diagnosis by thinking up ideas for cancer comedy movies with his best friend, actor Seth Rogen. Rogen and actor Joseph Gordon-Levitt now star in a film based on Reiser's life. Both Gordon-Levitt and Reiser join Fresh Air for a conversation about the film.

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