Terry Gross

Peter D. Kramer's new book is Against Depression. In it, the author of Listening to Prozac puts forth an understanding of depression as a modern scourge. Kramer argues that depression should be considered a disease — and treated as such. Kramer is a clinical professor of psychiatry at Brown University.

David Shore and Dr. David Foster combine to be the driving force behind the new medical series House, on FOX TV. Shore is the executive producer; Foster is the medical consultant and writes for the series. On the show, medical maladies play the role of villain. The hero is an irreverent and controversial doctor who trusts no one.

Husband and wife actors Felicity Huffman and William H. Macy have collaborated on the new offbeat feature Transamerica. Macy is the executive producer on the project, which features Huffman as a male-to-female transsexual who is contacted by the son she never knew she fathered.